Point-of-care imaging system for early diagnosis in low resource setting
Compact and cost-effective imaging system (hardware and software) for early diagnosis of disease and cancer in resource-limited setting
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portfolio
Cancer screening in low resource setting using the customized system
Oral cancer screening campaign in Dimapur, India using customized system
AI algorithm implementation on the cloud server and edge device
AI algorithm implementation on the cloud server and edge device
Uncertainty-informed trustworthy medical AI solutions
Uncertainty-informed trustworthy medical AI solutions
Interpretable Artificial Intelligence for disease and cancer image analysis
Interpretable Artificial Intelligence for disease and cancer image analysis
publications
Patent: Organism fluorescent three-dimensional imaging system and application
Published in Patent, 2011
Mu Ying, Wang Ying, Song Bofan, Zhang Jun, Jin Wei, Jin Qinhan
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Patent: Handheld general microfluidic chip real-time detection device and application
Published in Patent, 2013
Mu Ying, Song Bofan, Jin Wei, Yu Bingwen
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Patent: A kind of apparatus and method being applied to gradient temperature and controlling
Published in Patent, 2014
Mu Ying, Yu Bingwen, Zhu Qiangyuan, Song Bofan, Jin Qinhan, Jin Wei
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In vivo near-infrared fluorescence three-dimensional positioning system with binocular stereovision
Published in Journal of biomedical optics, 2015
Song Bofan, Wei Jin, Ying Wang, Qinhan Jin, and Ying Mu. “In vivo near-infrared fluorescence three-dimensional positioning system with binocular stereovision.” Journal of Biomedical Optics 19, no. 11 (2014): 116002-116002.
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A nanoliter self-priming compartmentalization chip for point-of-care digital PCR analysis
Published in Biomedical microdevices, 2015
Song, Qi, Yibo Gao, Qiangyuan Zhu, Qingchang Tian, Bingwen Yu, Song Bofan, Yanan Xu et al. “A nanoliter self-priming compartmentalization chip for point-of-care digital PCR analysis.” Biomedical microdevices 17 (2015): 1-8.
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Preparation of functionalized polymersomes and the in vivo imaging
Published in International Journal of Polymeric Materials and Polymeric Biomaterials, 2015
Li Zuhong, Tingting Pan, Wei Jin, Song Bofan, Yibo Gao, Maokai Yuan, Hao Ren, Tao Zhang, and Ying Mu. “Preparation of functionalized polymersomes and the in vivo imaging.” International Journal of Polymeric Materials and Polymeric Biomaterials 64, no. 3 (2015): 117-124.
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Rapid absolute determination platform of nucleic acid for point-of-care testing
Published in Chemical Research in Chinese Universities, 2015
Song Bofan, Wei Jin, Qi Song, Qinhan Jin, and Ying Mu. “Rapid absolute determination platform of nucleic acid for point-of-care testing.” Chemical Research in Chinese Universities 31, no. 4 (2015): 519-525.
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Automatic classification of dual-modalilty, smartphone-based oral dysplasia and malignancy images using deep learning
Published in Biomedical Optics Express, 2018
Song Bofan, Sumsum Sunny, Ross D. Uthoff, Sanjana Patrick, Amritha Suresh, Trupti Kolur, G. Keerthi et al. “Automatic classification of dual-modalilty, smartphone-based oral dysplasia and malignancy images using deep learning.” Biomedical optics express 9, no. 11 (2018): 5318.
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Point-of-care, smartphone-based, dual-modality, dual-view, oral cancer screening device with neural network classification for low-resource communities
Published in Plos one, 2018
Uthoff. Ross,* Song Bofan,* Sumsum Sunny,* Sanjana Patrick, Amritha Suresh, Trupti Kolur, G. Keerthi et al. “Point-of-care, smartphone-based, dual-modality, dual-view, oral cancer screening device with neural network classification for low-resource communities.” PloS one 13, no. 12 (2018): e0207493.
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Small form factor, flexible, dual-modality handheld probe for smartphone-based, point-of-care oral and oropharyngeal cancer screening
Published in Journal of biomedical optics, 2019
Uthoff. Ross D.,* Song Bofan,* Sumsum Sunny, Sanjana Patrick, Amritha Suresh, Trupti Kolur, Keerthi Gurushanth et al. “Small form factor, flexible, dual-modality handheld probe for smartphone-based, point-of-care oral and oropharyngeal cancer screening.” Journal of biomedical optics 24, no. 10 (2019): 106003-106003.
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Deep convolutional neural network phase unwrapping for fringe projection 3d imaging
Published in Sensors, 2020
Liang Jian, Junchao Zhang, Jianbo Shao, Song Bofan, Baoli Yao, and Rongguang Liang. “Deep convolutional neural network phase unwrapping for fringe projection 3D imaging.” Sensors 20, no. 13 (2020): 3691.
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Point-of-care, multispectral, smartphone-based dermascopes for dermal lesion screening and erythema monitoring
Published in Journal of biomedical optics, 2020
Uthoff Ross D., Song Bofan, Melody Maarouf, Vivian Y. Shi, and Rongguang Liang. “Point-of-care, multispectral, smartphone-based dermascopes for dermal lesion screening and erythema monitoring.” Journal of biomedical optics 25, no. 6 (2020): 066004.
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MicroLED chromatic confocal microscope
Published in Optical Letters, 2021
Li Shaobai, Song Bofan, Tyler Peterson, Jian Hsu, and Rongguang Liang. “MicroLED chromatic confocal microscope.” Optics Letters 46, no. 11 (2021): 2722-2725.
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Mobile-based oral cancer classification for point-of-care screening
Published in Journal of Biomedical Optics, 2021
Song Bofan, Sumsum Sunny, Shaobai Li, Keerthi Gurushanth, Pramila Mendonca, Nirza Mukhia, Sanjana Patrick et al. “Mobile-based oral cancer classification for point-of-care screening.” Journal of biomedical optics 26, no. 6 (2021): 065003-065003.
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mHealth-Based Point-Of-Care Diagnostic Tool for Early Detection of Oral Cancer and Pre-Cancer Lesions in a Low-Resource Setting
Published in SSRN Preprints, 2021
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Bayesian deep learning for reliable oral cancer image classification
Published in Biomedical Optics Express, 2021
Song Bofan, Sumsum Sunny, Shaobai Li, Keerthi Gurushanth, Pramila Mendonca, Nirza Mukhia, Sanjana Patrick et al. “Bayesian deep learning for reliable oral cancer image classification.” Biomedical Optics Express 12, no. 10 (2021): 6422.
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Classification of imbalanced oral cancer image data from high-risk population
Published in Journal of Biomedical Optics, 2021
Song Bofan, Shaobai Li, Sumsum Sunny, Keerthi Gurushanth, Pramila Mendonca, Nirza Mukhia, Sanjana Patrick et al. “Classification of imbalanced oral cancer image data from high-risk population.” Journal of biomedical optics 26, no. 10 (2021): 105001-105001.
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Interpretable deep learning approach for oral cancer classification using guided attention inference network
Published in Journal of Biomedical Optics, 2022
Figueroa Kevin,* Song Bofan,* Sumsum Sunny, Shaobai Li, Keerthi Gurushanth, Pramila Mendonca, Nirza Mukhia et al. “Interpretable deep learning approach for oral cancer classification using guided attention inference network.” Journal of biomedical optics 27, no. 1 (2022): 015001-015001.
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Structured light dark-field microscope
Published in arXiv preprint, 2022
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Diagnosis of paediatric tuberculosis by optically detecting two virulence factors on extracellular vesicles in blood samples
Published in Nature Biomedical Engineering, 2022
Zheng Wenshu, Sylvia LaCourse, Song Bofan, Dhiraj Kumar Singh, Mayank Khanna, Juan Olivo, Joshua Stern et al. “Diagnosis of paediatric tuberculosis by optically detecting two virulence factors on extracellular vesicles in blood samples.” Nature biomedical engineering 6, no. 8 (2022): 979-991.
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Field validation of deep learning based Point-of-Care device for early detection of oral malignant and potentially malignant disorders
Published in Scientific Reports, 2022
Birur N. Praveen,* Song Bofan,* Sumsum P. Sunny,* Pramila Mendonca, Nirza Mukhia, Shaobai Li, Sanjana Patrick et al. “Field validation of deep learning based Point-of-Care device for early detection of oral malignant and potentially malignant disorders.” Scientific Reports 12, no. 1 (2022): 14283.
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Exploring uncertainty measures in convolutional neural network for semantic segmentation of oral cancer images
Published in Journal of Biomedical Optics, 2022
Song Bofan, Shaobai Li, Sumsum Sunny, Keerthi Gurushanth, Pramila Mendonca, Nirza Mukhia, Sanjana Patrick et al. “Exploring uncertainty measures in convolutional neural network for semantic segmentation of oral cancer images.” Journal of Biomedical Optics 27, no. 11 (2022): 115001.
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Interpretable and Reliable Oral Cancer Classifier with Attention Mechanism and Expert Knowledge Embedding via Attention Map
Published in Cancers, 2023
Song Bofan, Chicheng Zhang, Sumsum Sunny, Dharma Raj Kc, Shaobai Li, Keerthi Gurushanth, Pramila Mendonca et al. “Interpretable and Reliable Oral Cancer Classifier with Attention Mechanism and Expert Knowledge Embedding via Attention Map.” Cancers 15, no. 5 (2023): 1421.
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Performance of Automated Oral Cancer Screening Algorithm in Tobacco Users vs. Non-Tobacco Users
Published in Applied Sciences, 2023
Yang Susan Meishan, Song Bofan, Cherie Wink, Mary Abouakl, Thair Takesh, Michelle Hurlbutt, Dana Dinica, Amber Davis, Rongguang Liang, and Petra Wilder-Smith. “Performance of Automated Oral Cancer Screening Algorithm in Tobacco Users vs. Non-Tobacco Users.” Applied Sciences 13, no. 5 (2023): 3370.
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Clinical assessment of a low-cost, hand-held, smartphone-attached intraoral imaging probe for 5-aminolevulinic acid photodynamic therapy monitoring and guidance
Published in Journal of Biomedical Optics, 2023
Khan, Shakir, Song Bofan, Srivalleesha Mallidi, Shaobai Li, Hui Liu, M. A. Bilal Hussain, Shaista Siddiqui et al. “Clinical assessment of a low-cost, hand-held, smartphone-attached intraoral imaging probe for 5-aminolevulinic acid photodynamic therapy monitoring and guidance.” Journal of Biomedical Optics 28, no. 8 (2023): 082809-082809.
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Inter-observer agreement among specialists in the diagnosis of oral potentially malignant disorders and oral cancer using store-and-forward technology
Published in Clinical Oral Investigations, 2023
Keerthi, Gurushanth, Nirza Mukhia, Sumsum P. Sunny, Bofan Song, Shubhasini A. Raghavan, Shubha Gurudath, Pramila Mendonca et al. “Inter-observer agreement among specialists in the diagnosis of oral potentially malignant disorders and oral cancer using store-and-forward technology.” Clinical Oral Investigations 27, no. 12 (2023): 7575-7581.
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Classification of Mobile-Based Oral Cancer Images Using the Vision Transformer and the Swin Transformer
Published in Cancers, 2024
Song, Bofan, Dharma Raj Kc, Rubin Yuchan Yang, Shaobai Li, Chicheng Zhang, and Rongguang Liang. “Classification of Mobile-Based Oral Cancer Images Using the Vision Transformer and the Swin Transformer.” Cancers 16, no. 5 (2024): 987.
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Integrating artificial intelligence with smartphone-based imaging for cancer detection in vivo
Published in Biosensors and Bioelectronics, 2024
Song, Bofan, and Rongguang Liang. “Integrating artificial intelligence with smartphone-based imaging for cancer detection in vivo.” Biosensors and Bioelectronics 271 (2025): 116982.
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talks
Development of a dual-modality, dual-view smartphone-based imaging system for oral cancer detection
Published:
Mobile Oral Cancer Image Classification based on Efficient Deep Learning for Low-resource Settings
Published: